[learn_more caption=”Changquan Calvin Sun”] Dr. Sun is currently an Associate Professor of Pharmaceutics at the University of Minnesota, USA. He worked in the pharmaceutical industry (Amgen and Pfizer, 2000 – 2008) prior to joining the same department as an Assistant Professor in 2008. Dr. Sun received his Ph.D. in Pharmaceutics in 2000 under the guidance of late Prof. David Grant at University of Minnesota. His research focuses on 1) crystal and particle engineering for superior pharmaceutical properties, including powder flow and tabletability, solubility, and staility; 2) understanding and control of common pharmaceutical unit operations, e.g., blending, granulation, and tableting. Dr. Sun is an expert in the areas of solid-state science, tablet formulation design, and powder technology. He is an author of more than 60 peer reviewed papers.[/learn_more]

Powder compaction is a critical step for manufacture pharmaceutical tablets for successful drug  delivery. Despite the long history of powder compaction, there are many knowledge gaps due to the complex nature of this process. Compaction simulation serves as a useful tool for guiding the design of a tablet formulation that is manufacturable at the commercial scale. In this presentation, some fundamental aspects of powder compaction will be presented and application of compaction simulation in powder compaction research will be discussed with examples.