Ajaz S. Hussain, Ph.D.

A compact is a dense structure, closely packed as in a tablet; it is also an agreement or covenant to care and to assure.  Might the science and practice of compaction pharmaceutics hold a mirror to the broader social challenge we, the members of a community of knowledge, [must] confront?  “You’re grounded until your behavior and grades improve” is a familiar childhood experience for many.  Considering the lessons in tri-axial compression of formulations prone to capping and delaminating, this talk experiments with the compaction of three axioms on managing knowledge, acknowledging conflicting interests, and experiential learning to overcome hurdles to continual improvement.  Systematic improvement, for instance, following Annual Product [and performance] Review, often cycles back to familiar why bother excuses – it is “FDA Approved” and the “process validated.”  Considering such excuses as an “immunity to change,” an indicator of immaturity, the talks conclude with some SMART considerations for continuous development. A social conversation grounded in technical know-how can help all of us be suitable and capable of generating the care and assurance a pharmaceutical compact must deliver.