From small-scale powder characterisation to optimal processing

[learn_more caption=”Dr. Pirjo Tajarobi”] Dr. Pirjo Tajarobi (née Luukkonen) received her Ph.D. in Pharmaceutics from the University of Helsinki (Finland) in 2001. She joined AstraZeneca Mölndal, Sweden 2001 and she has worked in the area of Product Development, PAT and Material Science. Currently Dr. Tajarobi is working as an Associate Principal Scientist in the Drug Product Manufacture. She is an Associate Professor both at the University of Helsinki and Åbo Akademi University in Finland. She is an expert in the areas of high-shear wet granulation, continuous wet granulation, roller compaction and powder flow characterisation. She has published more than 18 peer-reviewed papers in these areas.[/learn_more]

During processing of new drug compounds material related problems are quite common. This has an immediate impact on the work within product development, as well as on manufacturability during scale-up and large scale production. A possible early identification of descriptors for material related issues would save both time and resources. This talk will focus on the small scale characterization methods and predictive models typical for direct compression, roller compaction and wet granulation processes.