[learn_more caption=”Ilgaz Akseli, Ph.D.”] Ilgaz Akseli is a Principal Scientist in the Pharmaceutical Development department in Boehringer-Ingelheim, Ridgefield, CT. He is the head of the Formulation Material Profiling and Computational Modeling Labs. Two labs are in the global level and his team is guiding and supporting the formulation and process development for drug candidates in assigned therapeutic areas. Dr. Akseli earned his BSc degree in Mechanical Engineering with a focus on Design of Powder Compaction. He has two MSc degrees; one is in Materials Science and Engineering from University College London with a focus on Metal Powder Compaction and the other degree is in Business Management from London School of Economics with a focus on Lean Six Sigma, UK. He earned his PhD degree in Mechanical Engineering from Clarkson University, USA. He did his Post-doctoral studies at Rutgers University in the Engineering Research Center (ERC) for Particulate Systems and Pharmaceuticals. He has authored of 27 refereed journal papers, 33 conference papers & presentations, 6 scientific magazine articles, 2 book chapters & 2 patents.[/learn_more]

Structures are ubiquitous in all materials systems from the subatomic to the macroscopic level. The key question is what feature at a given scale is persistent at the next level of observation. Conventional pharmaceutical solid dosage forms are being optimized and in some cases redesigned in response to drug delivery challenges. This talk will provide a high level overview of how advanced material profiling and computational modeling approaches can be used to guide formulation development/risk-based formulation design and trouble-shoot manufacturing issues. In this talk, examples from early development to commercial manufacture will be shown and discussed.