[learn_more caption=”Charley Wu”] Biography: Prof. Chuan-Yu (Charley) Wu is a professor in Chemical Engineering at the Department of Chemical and Process Engineering and a member of the Academy of Pharmaceutical Sciences (APS).  Prof. Wu is currently an executive editor for Powder Technology, and the coordinator of  a EU FP7 Initial Training Network (ITN) consortium on the development of in silico models for roll compaction, which consists of 14 partners from 7 EU countries. He has expertise in discrete element analysis, multiscale modelling and simulations, pharmaceutical engineering, particle technology and granular dynamics.  Prof. Wu has been working closely with the global pharmaceutical industry in developing advanced numerical modelling techniques for pharmaceutical application. He edited two books entitled “Discrete Element Modelling of Particulate Media” and “Particulate Materials: Synthesis, Characterisation, Processing and Modelling” published by RSC publishing, four journal special issues and published over 100 scientific papers. Prof. Wu obtained his BSc. and MSc. from Huazhong University of Science and Technology (Wuhan, China) in 1994 and 1997, respectively, and his PhD. on finite element analysis of particle impact problems from Aston University (Birmingham, UK) in 2002. He worked as a postdoctoral research associate at the Department of Engineering in the University of Leicester from 2001 to 2003, and at Pfizer Institute for Pharmaceutical Materials Science, Department of Materials Science and Metallurgy in the University of Cambridge between 2003 and 2005. In 2005, Prof. Wu was awarded an prestigious EPSRC Advanced Research Fellowship and joined the University of Birmingham. He was appointed as a senior lecturer in the School of Chemical Engineering at Birmingham in December 2008, prior to his present position as a professor in chemical engineering at the University of Surrey in January 2013.[/learn_more]

 Abstract: Roll compaction is a commonly used dry granulation process in pharmaceutical, fine chemical and agrochemical industries for materials sensitive to heat or moisture. In this talk, an overview of mechanistic models for roll compaction will be presented, including first principle models, discrete element models and continuum models (i.e. finite element models). The capability and limitations of each model will be discussed. Recent advances in integrating these models will also be presented.