2014 Forum Agenda: Philadelphia, PA, USA

The following schedule is tentative. Check back often for updates and revisions.

Monday, June 9th, 2014

5:00p- 7:00pWalking Tour
Sponsored by Huxley Bertram
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7:00p- 9:00pWelcome Reception at the Chemical Heritage Foundation
Sponsored by Huxley Bertram
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Tuesday, June 10th 2014

CSF Day 1
8:00 – 8:50amBreakfast and Registration
8:50 – 9:00Welcome from the CSF Programming Committee
Modeling and Simulation
9:00 – 9:40Keynote: Antonios Zavaliangos, Ph.D, Drexel University,
Successes and roadblocks for effective use of modeling in tableting applications
9:40 – 10:05Alberto Cuitino, Ph.D., Rutgers University,
Modeling compact strength of granular materials
10:05 – 10:30 Sherif Badawy, Bristol Myers Squibb
Application of the Drucker-Prager Cap model to assess the risk in tablet compaction
10:30 – 10:50Break
10:50 – 11:15Jerry Klinzing, Ph.D., Merck,
Computational design of tablet microstructures
11:15 – 11:40Valantis Tsinginos, Ph.D., Drexel University,
Discrete Element Model: toward a suitable method for modeling the compaction process and compact properties
11:40 – 12:05pmCetin Cetinkaya, Ph.D., Clarkson University,
Real-time in-die compaction monitoring
12:05 – 12:30Lunch
Materials Characterization
1:30 – 2:10Keynote: Changquan Calvin Sun, Ph.D, University of Minnesota,
Challenges and opportunities in pharmaceutical powder compaction
2:10 – 2:35Rahul V. Haware, Ph.D., Campbell University
DM2 approach for the evaluation and prediction of powder compaction properties
2:35 – 3:00Pingjun Tang, Ph.D., Vertex Pharmaceuticals
Application of Compaction Simulation towards a Multi‐Dimensional Understanding of Compression Behavior
3:00 – 3:20Break
3:20 – 3:45 Jeffrey Katz, Duquesne University
A material-sparing method for assessment of powder deformation characteristics using data collected during a single compression decompression cycle
3:45 – 4:10Sayantan Chattoraj, Ph.D., GSK
Manufacturability comparison of granules from batch vs. continuous wet granulation assessed by API sparing approaches
4:10 – 4:35Frederick Osei-Yeboah, University of Minnesota,
The development of compressible beads for manufacturing controlled release tablet
4:35 – 5:00Round Table
5:00p – 7:00Poster Presentations and Cocktail Reception
Hosted by Drexel
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Sponsored by Colorcon
Colorcon
7:00 – 9:30Dinner and Poster Presentation Awards
Sponsored by Colorcon & MEDELPHARM
Colorcon

Wednesday, June 11th 2014

CSF Day 2
8:30-9:00Breakfast
Process Engineering
9:00 – 9:45

Keynote: Adam Procopio, Ph.D., Merck,
From Particle Properties to Process Engineering
9:45-10:15

Ilgaz Akseli, Ph.D., Boehringer- Ingelheim
Integrated materials profiling and computational modeling in drug product development
10:15-10:35
Break
10:35-11:10

Bhavishya Mittal, PhD. & Sree Haritha Chalasani, Takeda
Evaluating High Shear Wet Granulation Design Space Using Compaction Simulator
11:10 – 11:40
Joseph Kushner, IV, Ph.D., Pfizer
Evaluating lubrication sensitivity of pharmaceutical powders to improve lubricant mixing process scale-up
11:40 – 12:05
Round Table: Process Engineering
12:05 – 12:30
Round Table: Manufacturer Discussion
12:30 – 1:30Lunch
Non-Pharmaceutical Applications
1:30 – 2:15Keynote: Prof. Virendra Puri, Pennsylvania State University
The Cubical Triaxial Tester (CTT) - CTT overview & recent results
2:15 – 3:00Warren C. Oliver, Ph.D. Chief Scientist, Nanomechanics Inc., Adjunct Professor, University of Tennessee
Nanoindentation Testing: Background and Recent Advances
3:00 – 3:15Break
3:15 – 4:00Antonios Kontsos, Ph.D. Assistant Professor, Director, Theoretical & Applied Mechanics Group, Drexel University
Advances in multimodal NDE methods and technologies for industrial applications
4:00 – 4:45Round Table: Compaction Perspectives from Outside Pharma
4:45 – 5:00Concluding Remarks

Program Committee

Organizing Committee